B-ENT

Clarithromycin induced reversible sensorineural hearing loss

1.

ENT Department of General Hospital of Nikea, Piraeus, Greece

2.

Obstetrics & Gynaecology Department of General Hospital “Papageorgiou”, Thessaloniki, Greece

B-ENT 2011; 7: 127-130
Read: 1033 Downloads: 522 Published: 14 February 2020

Clarithromycin induced reversible sensorineural hearing loss. Objective: We present a rare case of reversible sensorineural hearing loss caused by clarithromycin.

Methods: We present a case report of hearing loss following clarithromycin administration; we also review the current literature and case reports concerning macrolides and, in particular, clarithromycin induced hearing loss.

Results: A young pregnant woman presented with sensorineural hearing loss after clarithromycin intake. The subject’s hearing returned to normal limits after drug discontinuation and short-term treatment with low dose steroids.

Conclusion: Newer macrolides are considered to be safer regarding ototoxic effects, and a few cases have been previously described. The present case adds to the body of knowledge concerning clarithromycin ototoxicity. Clinicians should be aware of this rare complication and a thorough otologic history should be established prior to macrolide administration. A baseline audiogram and close observation for patients at higher risk is suggested to identify patients with prior hearing loss and serve as baseline for future reference.

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EISSN 2684-4907