Original Article

Is Baseline SNOT-22 Able to Predict the Need for Nose or Sinus Surgery? A Prospective Multicenter Study


Department of ENT, ULG University Hospital of Liege, Liege, Belgium


Department of ENT, ULB Saint-Pierre University Hospital, Liege, Belgium


Department of Public Health, Biostatistics, University of Liege, Liege, Belgium


Department of ENT, UCL University Hospital Namur, Liege, Belgium

B-ENT 2022; 18: 154-161
DOI: 10.5152/B-ENT.2022.21699
Read: 832 Downloads: 367 Published: 01 July 2022

Objective: Developing reliable and easy-to-use telemedicine tools is essential in primary care. We sought whether Sino-Nasal Outcome Test-22 could predict the need for surgery and localize pathology of rhinology patients and healthy volunteers solely based on the pattern of the baseline Sino-Nasal Outcome Test-22.

Methods: Baseline Sino-Nasal Outcome Test-22 from 66 healthy volunteers and 383 rhinology patients was collected blindly prior to diagnosis. Participants were then categorized into 4 groups according to their diagnosis: control, no surgery (i.e. medical condition), functional nose surgery, and sinus surgery. The difference between groups was assessed by a multinomial logistic regression adjusted for age, gender, asthma, tobacco, history of nose surgery, and trauma.

Results: The 22 items of Sino-Nasal Outcome Test differed significantly among the 4 groups (P < .05). Control subjects showed the lowest Sino-Nasal Outcome Test-22 scores for all items. Patients requiring sinus surgery and those listed for nose surgery exhibited a specific pattern of Sino-Nasal Outcome Test-22 score. Nasal and extranasal rhinology symptoms were more specific to the diagnosis than psychological or sleep dysfunction domains.

Conclusion: Distinct Sino-Nasal Outcome Test-22 patterns were associated with subjects’ diagnosis. SNOT-22 was not only able to score severity but could also localize the disease, orientate the diagnosis, and predict the need for surgical treatment. The Sino-Nasal Outcome Test-22 may be the easy telemedicine tool the primary care needs for a better referral pattern.

Cite this article as: Pottier L, De Dorlodot C, Ansari E, et al. Is baseline SNOT-22 able to predict the need for nose or sinus surgery? A prospective multicenter study. B-ENT 2022;18(3):154-161.

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