- A prospective study of long-term dysphagia following total laryngectomy
- C. T. Chone , A. L. Spina , I. H. Barcellos , H. H. Servin and A. N. Crespo
- 1D epartment of Otolaryngology, Head and Neck, D epartment of Radiology, University of Campinas, Unicamp,
Campinas, São Paulo, Brazil
- Cancer of larynx; total laryngectomy; dysphagia; swallowing; larynx
- 103 - 109
- A prospective study of long-term dysphagia following total laryngectomy. Objective: To evaluate the degree
of dysphagia in patients before and after total laryngectomy using the Performance Status Scale for Head and Neck
Cancer Patients (PSS) and to determine the effects of post-operative radiation therapy, neck dissection, and pharyn-
goesophageal spasm on PSS scores.
Methods: We performed a controlled, prospective study at a tertiary referral university hospital. Twenty consecutive
patients undergoing laryngectomy were included. Patients were followed for at least two years post-operative, without
evidence of local, regional, or distant disease. Only patients with squamous cell carcinoma limited to the endolarynx
requiring total laryngectomy with or without elective neck dissection for surgical management of cancer and with no
pre-operative treatment were included. Dysphagia was evaluated by PSS prior to surgery and again two years post-
operatively with an emphasis on eating in public and normalcy of diet domains. Video fluoroscopic evaluation of
swallowing was performed one year after treatment.
Results: The relative number of patients with low mean scores in PSS (i.e. usually swallow paste of fluid food in
presence of some selected persons or alone; <50) increased after total laryngectomy (p = 0.04). Patients with lower
scores reported more frequent spasm of the pharyngoesophageal segment (p = 0.005). Mean scores of both domains
decreased after surgery (p<0.05).
Conclusion: Eating in public and normalcy of diet scores decreased in 50% of patients after total laryngectomy.
Trial Registration: controlled-trials.com Identifier: ISRCTN20496103
- Vol. 7, 2011, 2nd trimester
A prospective study of long-term dysphagia following total laryngectomy