Title:
Biofilm colonisation in nasolacrimal stents
Authors:
A. Ibáñez , A. Trinidad , J. R. García-Berrocal , D. Gómez , J. San Román and R. Ramírez-Camacho
Institutions:
1Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Organic Chemistry Institute Lora-Tamayo, Spanish National Research Council (CSIC), Madrid, Spain
Keywords:
Biofilms; lacrimal duct obstruction; epiphora; dacryocystitis; environmental scanning electron microscopy
Pages:
7 - 10
Abstract:
Biofilm colonisation in nasolacrimal stents. Problem/Objective: Nasolacrimal duct obstruction is a common problem. A Song stent is a useful and simple treatment with low morbidity. However, the success rate is limited, especially in long-term follow-up. The aim of the present study is to determine the presence of biofilms in failing nasolacrimal stents. Methodology: Thirty-three polyurethane nasolacrimal stents were implanted between January 2006 and December 2007 using Song’s technique. Patients were followed for a mean of 21.5 months (range 11-30 months). Removed nasolacrimal stents were preserved in saline and examined using environmental scanning electron microscopy (ESEM). Results: Eighteen nasolacrimal stents were removed because of the failure of the device (follow-up range 11-30 months). Seven stents were recovered for this study. Biofilms were identified in all the specimens studied. Five prostheses showed occlusion caused by mucus or granulation tissue. Conclusions: Biofilm colonisation of nasolacrimal stents could play a major role in prosthetic failure leading to stent occlusion. Mucus, granulation tissue and irregularities of the biomaterial are factors that facilitate biofilm colonisation. Non-stick material for newly developed stents or drugs capable of destroying the polysaccharide matrix should be considered as future therapeutic options.
Issue:
Vol. 7, 2011, 1st trimester


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Biofilm colonisation in nasolacrimal stents