Biofilm colonisation in nasolacrimal stents
A. Ibáñez , A. Trinidad , J. R. García-Berrocal , D. Gómez , J. San Román and R. Ramírez-Camacho
1Department of Otorhinolaryngology, Hospital Universitario Puerta de Hierro-Majadahonda, Madrid, Spain; Organic Chemistry Institute Lora-Tamayo, Spanish National Research Council (CSIC), Madrid, Spain
Biofilms; lacrimal duct obstruction; epiphora; dacryocystitis; environmental scanning electron microscopy
7 - 10
Biofilm colonisation in nasolacrimal stents. Problem/Objective: Nasolacrimal duct obstruction is a common problem. A Song stent is a useful and simple treatment with low morbidity. However, the success rate is limited, especially in long-term follow-up. The aim of the present study is to determine the presence of biofilms in failing nasolacrimal stents. Methodology: Thirty-three polyurethane nasolacrimal stents were implanted between January 2006 and December 2007 using Song’s technique. Patients were followed for a mean of 21.5 months (range 11-30 months). Removed nasolacrimal stents were preserved in saline and examined using environmental scanning electron microscopy (ESEM). Results: Eighteen nasolacrimal stents were removed because of the failure of the device (follow-up range 11-30 months). Seven stents were recovered for this study. Biofilms were identified in all the specimens studied. Five prostheses showed occlusion caused by mucus or granulation tissue. Conclusions: Biofilm colonisation of nasolacrimal stents could play a major role in prosthetic failure leading to stent occlusion. Mucus, granulation tissue and irregularities of the biomaterial are factors that facilitate biofilm colonisation. Non-stick material for newly developed stents or drugs capable of destroying the polysaccharide matrix should be considered as future therapeutic options.
Vol. 7, 2011, 1st trimester

Biofilm colonisation in nasolacrimal stents