Title:
Malignant ectomesenchymoma of the paranasal sinuses with proptosis
Authors:
A.-S. Vinck , B. Lerut , R. Hermans , S. Nuyts , R. Sciot and M. Jorissen
Institutions:
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Belgium; D epartment of Otorhinolaryngology, Head and Neck Surgery, Sint-Jan General Hospital, Bruges, Belgium; Department of Radiology,University Hospitals Leuven, Belgium; Department of Radiation Oncology, University Hospitals Leuven, Belgium; Department of Pathology, University Hospitals Leuven, Belgium
Keywords:
Malignant ectomesenchymoma; soft tissue tumour; neuroectodermal elements; mesenchymal neoplastic elements
Pages:
201 - 204
Abstract:
Malignant ectomesenchymoma of the paranasal sinuses with proptosis. Problem: A 36-year-old woman presented with a feeling of pressure in the right orbit and proptosis of the right eye after a “common cold”. Methodology: Computed tomography (CT) of the maxillofacial region revealed, and endoscopy confirmed, a mass in the right ethmoid sinus, eroding the lamina papyracea and extending into the orbit. Pathology of multiple biopsies revealed a nasal neoplasm composed of neuroectodermal and mesenchymal neoplastic elements, suggestive of a malignant ectomesenchymoma (MEM). Magnetic resonance imaging was used for MEM staging. Computed tomography of the chest and abdomen show no evidence of distant metastases. Results: Due to the intracranial and intraorbital extension of the tumour, radical surgery was not an option. Appropriate chemotherapy (6 cycles of vincristine/ifosfamide/adriamycin and 2 cycles of vincristine/ifosfamide/cisplatin) and intensity-modulated radiation therapy were administered. Conclusion: Twenty-eight months after treatment, there was no evidence of residual or metastatic disease.
Issue:
Vol. 7, 2011, 3rd trimester


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Malignant ectomesenchymoma of the paranasal sinuses with proptosis