Title:
Metastasis of a small cell carcinoma from undetected origin to the pituitary gland – The otolaryngologist’s view
Authors:
Ph. Eloy*, A-S. Evrard*, J. Donckier**, C. Godfraind****, Th. Gustin***, St. Collet*, Ph. Rombaux* and B. Bertrand*
Institutions:
*Department of Otorhinolaryngology, Head and Neck Surgery, **Department of Endocrinology, ***Department of Neurosurgery, University Hospital of Mont-Godinne, Université Catholique de Louvain, Yvoir, ****Department of Histopathology, University Hospital Saint Luc, Bruxelles, Belgium.
Keywords:
Small cell lung carcinoma; pituitary metastasis; undetected origin
Pages:
159 - 163
Abstract:
Metastasis of a small cell carcinoma from undetected origin to the pituitary gland – The otolaryngologist’s view. Tumour metastasis to the anterior pituitary-hypothalamic area is rare. We present a patient who had severe headache, bitemporal quadrant hemianopsia and an expanding mass in the sella turcica as revealed by MRI. Partial resec- tion via a transsphenoidal approach was performed and postoperative radiation therapy was initiated. Immuno- histochemical investigation identified the tumour as a metastatic small cell carcinoma whose primary site remained undetected for more than 12 months despite repeated oncological evaluations. We reviewed the literature on metastatic disease of the pituitary gland.
Issue:
Vol. 1, 2005, 3rd trimester


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Metastasis of a small cell carcinoma from undetected origin to the pituitary gland – The otolaryngologist’s view