Title:
Nasal NK/T-cell lymphoma in the paediatric population. two case reports
Authors:
I. Zeglaoui*, M. Belcadhi*, B. Sriha** and K. Bouzouita*
Institutions:
*Department of Otorhinolaryngology, **Department of Anatomic Pathology, Farhat Hached Hospital, Sousse, Tunisia
Keywords:
Nose; paranasal sinuses; T-cell lymphoma; NK-cell lymphoma; Epstein-barr virus
Pages:
119 - 123
Abstract:
Nasal NK/T-cell lymphoma in the paediatric population. two case reports. Nasal natural killer (NK)/T-cell lymphoma is an uncommon disease, and only a few paediatric cases are found in the literature. We report 2 cases of NK/T-cell lymphoma occurring in children. The primary site was the the nasal cavity in the first case (5-year-old girl) and the tonsil in the second case (4-year-old boy). Histological study showed a polymorphic neoplastic infiltrate with an angioinvasive pattern and T-cell phenotype. Ebstein-barr virus infection was established by in situ hybridization. Both underwent an aggressive chemotherapy regimen. The outcome was favorable for the 4-year old boy; however, the 5-year- old girl died two months after diagnosis.
Issue:
Vol. 5, 2009, 2nd trimester


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Nasal NK/T-cell lymphoma in the paediatric population. two case reports