Title:
Prediction of oral appliance treatment outcome in obstructive sleep apna syndrome: a preliminary study
Authors:
K. Suzuki , S. Nakata , M. Tagaya , F. Yasuma , S. Moral , E. Miyao , S. Tsuiki and T. Nakashima
Institutions:
Department of Otorhinolaryngology, Graduate School of Medicine, Nagoya University, Nagoya, Japan and the department of Otorhinolaryngology, Japanese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan; Department of Otorhinolaryngology, Second Hospital, Fujita Health University School of Medicine, Nagoya, Japan; Department of Otorhinolaryngology, Graduate School of Medicine, Nagoya Univer4ity, Nagoya, Japan and the department of Otorhinolaryngology, Tosei General Hospital, Aichi, Japan; Department of Internal Medicine, National Hospital Organization Suzuka Hospital, Mie, Japan; 5Department of Otolaryngology-Head & Neck Surgery, The Medical City Hospital, Manila, Philippines and the department of Otorhinolaryngology, Second Hospital, Fujita Health University School of Medicine, Nagoya, Japan; 6Ars Orthodontics Clinic, Nagoya, Japan; Japan Somnology Center, Neuropsychiatric Research Institute, Tokyo, Japan; Department of Otorhinolaryngology, Graduate School of Medicine, Nagoya University, Nagoya, Japan.
Keywords:
Sleep apnea; mandibular advancement; body mass index; pharynx
Pages:
185 - 191
Abstract:
Prediction of oral appliance treatment outcome in obstructive sleep apna syndrome: a preliminary study. Objective: Predictors of treatment outcome of oral appliances (OAs) in patients with obstructive sleep apna syndrome (OSAS) are not known. There is a pressing need for simple, clinically useful tools to predict treatment outcome. This study aimed to identify predictors of successful OA therapy for OSAS, including evaluation of pharyngeal morphology, which can be measured during routine examination by an otorhinolaryngologist. Methodology: This was a prospective study of 26 OSAS patients treated with OAs. A favourable outcome was obtained in 14 patients (responders) but not in 12 patients (nonresponders). The baseline patient characteristics and polysomnography and rhinopharyngeal findings were analysed. Results: Body mass index (BMI) was significantly lower in responders versus nonresponders (23.6±2.8 vs. 27.9± 4.7 kg/m ; p<0.05). Pharyngeal morphology, age, sex and nasal resistance did not differ between the groups. Multiple regression analysis showed that BMI was a significant predictor of improvement in the apna/hypopna index after OA treatment (p<0.05). Conclusion: Here we demonstrated that BMI is a favourable predictor of OA treatment outcome in OSAS patients. Among the OSAS patients, responders had wider retroglossal spaces than nonresponders.
Issue:
Vol. 10, 2014, 3rd trimester


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Prediction of oral appliance treatment outcome in obstructive sleep apna syndrome: a preliminary study