Title:
Syndrome of inappropriate antidiuretic hormone secretion due to recurrent oral cancer
Authors:
V. Danielides*, H J. Milionis**, V. Karavasilis**, E. Briasoulis*** and M. S. Elisaf**
Institutions:
*Department of Otorhinolaryngology Medical School, Demokritus University of Thrace, **Department of Internal Medicine, University of Ioannina, Ioannina, Greece, ***Division of Medical Oncology & Medical School, University of Ioannina, Ioannina, Greece
Keywords:
Hyponatremia; oral squamous cell carcinoma; paraneoplastic syndrome; syndrome of inappropriate secretion of antidiuretic hormone
Pages:
151 - 153
Abstract:
Syndrome of inappropriate antidiuretic hormone secretion due to recurrent oral cancerHyponatremia is a common metabolic disorder in clinical practice and is associated with significant morbidity and mortality, especially among the elderly. Hyponatremia resulting from the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) has been reported in association with neoplasia (including a few reports in patients with head and neck malig- nancies) and may represent a paraneoplastic condition. Patients with SIADH present with signs and symptoms that can- not be explained by the primary tumour mass effect or its metastases. We describe a 67-year-old male patient with oral squamous-cell carcinoma of recent recurrence admitted because of symptomatic severe hyponatremia resulting from SIADH and discuss the principles of the diagnostic approach and appropriate management.
Issue:
Vol. 1, 2005, 3rd trimester


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Syndrome of inappropriate antidiuretic hormone secretion due to recurrent oral cancer