Title:
Syndromic disorders in congenital hearing loss
Authors:
F. Lammens , N. Verhaert and C. Desloovere
Institutions:
1Department­of­Otorhinolaryngology,­Head­and­Neck­Surgery,­University­Hospitals­of­Leuven,­Leuven,­Belgium;­ 2University of Leuven, Department of Neurosciences, ExpORL Research Group, Leuven, Belgium
Keywords:
Newborn­hearing­loss;­syndrome;­etiology
Pages:
45 - 50
Abstract:
Syndromic disorders in congenital hearing loss.Objectives: To investigate the aetiology of congenital hearing loss detected by the universal neonatal hearing screening programme (Algo ) that was introduced in Flanders 15 years ago,­and,­more­specifically,­to­investigate­genetic­causes.­ Methodology:­Diagnostic­work-up­of­all­children­with­confirmed­hearing­loss­after­referral­by­the­Algo screening programme and screening at the neonatal intensive care unit (NICU) of our university hospital. Results:­A­hearing­loss­was­confirmed­in­505­of­the­569­neonates­(18%­from­NICU)­referred­between­1997­and­2011.­ After­further­examination,­a­genetic­origin­was­identified­in­84­(17%)­of­100­children­with­a­syndromic­hearing­loss.­The­ most frequent syndromes are discussed. Conclusion: A higher percentage of syndromic hearing loss was found than in the literature. This could be explained by the good cooperation with the human genetics department and the proportion of children retrieved from the neonatal intensive care unit.
Issue:
Suppl. 21, 2013


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Syndromic disorders in congenital hearing loss