Title:
Uncommon presentation of nasopharyngeal extramedullary plasmacytoma: a case report and literature review
Authors:
A. Manganaris*, B. Conn**, S. Connor*** and R. Simo****
Institutions:
*Department of Otorhinolaryngology – Head and Neck Surgery, **Department of Oral Pathology, ***Department of Radiology, ****Department of Otorhinolaryngology – Head and Neck Surgery, Guy’s and St Thomas’ Hospital NHS Foundation Trust, Guy’s Hospital, London SE1 9RT, UK
Keywords:
Extramedullary plasmacytoma; nasopharynx; multiple myeloma; plasma cell tumour; presentation
Pages:
143 - 146
Abstract:
Uncommon presentation of nasopharyngeal extramedullary plasmacytoma – case report and literature review. Objective: We report an exceptional presentation of extramedullary plasmacytoma of the nasopharynx without bone marrow involvement or other characteristics of multiple myeloma. Method: Case report and a review of the world literature concerning the clinical presentation, histopathological features, optimal treatment and prognosis of nasopharyngeal extramedullary plasmacytoma. Results: Reports of patients with symptomatic extramedullary plasmacytomas of the nasopharynx eventually being documented with histopathological evidence are not uncommon; however, the converse appears to be an extremely rare event. The patient was completely asymptomatic and following a paroxysm of coughing, expectorated a polypoidal nodule, which on histopathological investigation had features suggestive of extramedullary plasmacytoma. Conclusion: Although these tumours commonly present with significant nasal symptoms, this exceptional presentation in an asymptomatic patient has never been previously reported. Unusual presentations of rare tumours can pose considerable diagnostic dilemmas to both the surgeon and histopathologist. Awareness of these rarities is important to ensure the best patient care.
Issue:
Vol. 6, 2010, 2nd trimester


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Uncommon presentation of nasopharyngeal extramedullary plasmacytoma: a case report and literature review