Title:
Vagus nerve stimulation therapy induces laryngopharyngeal reflux: a preliminary evaluation
Authors:
G. A. Marciante , G. Felisati , C. Pipolo , A. Maccari , M. P. Canevini , M. De Gasperis , E. Zambrelli , A. Vignoli , F. Furia , A. M. Saibene,
Institutions:
San Paolo Hospital, Department of Health Sciences, Università degli Studi di Milano,Via Antonio di Rudinì, 20142 Milan, Italy; Regional Centre for Epilepsy, San Paolo Hospital, Department of Health Sciences, Università degli Studi di Milano, ViaAntonio di Rudinì, 20142 Milan, Italy
Keywords:
Drug resistant epilepsy, endoscopic reflux evaluation, reflux symptom index, reflux findings score
Pages:
275 - 279
Abstract:
Vagus nerve stimulation therapy induces laryngopharyngeal reflux: a preliminary evaluation. Objective: Vagus Nerve Stimulation (VNS) is an approved therapy for drug- and surgery-resistant epilepsy. Despite the vagal role in regulating gastric secretion, there are no reports focusing on the prevalence of laryngopharyngeal reflux (LPR) in the VNS-implanted population. Our study aims to evaluate the prevalence of t▯he disease in VNS-implanted patients. Methods: All patients underwent endoscopic Otolaryngological reflux assessment based on the reflux finding score (RFS) and contextual self-assessment of symptoms by means of reflux symptom index (RSI) questionnaire. Results: While only 3 out of 16 patients experienced symptomatic LPR (RSI>13), endoscopy documented LPR (RFS>7) in 12 out of 16 patients, there was no correlation between RSI and RFS (p.617). There has been an important trend between LPR findings since implantation was observed (p. 103). Conclusions: LPR has a significant prevalence in VNS-implanted patients.Aroutine Otolaryngological follow-up could allow the prompt diagnosis and treatment of LPR in this population.
Issue:
Vol. 13, 2017, 4th trimester


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Vagus nerve stimulation therapy induces laryngopharyngeal reflux: a preliminary evaluation