Title:
Wegener’s granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibroblastic tumour: a case report
Authors:
A.-S. Carpentier*, S. Riehm**, A. Charpiot*, A. Onea***, C. Debry* and Ph. Schultz*
Institutions:
*Department of Otorhinolaryngology, **Department of Radiology, ***Department of Histopathology, CHU Hautepierre, Strasbourg, France
Keywords:
Wegener’s granulomatosis; inflammatory myofibroblastic tumour; temporal bone; skull base
Pages:
135 - 138
Abstract:
Wegener’s granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibro- blastic tumour: a case report. Objective: To compare two potential diagnoses of a temporal bone pseudotumour: an inflammatory myofibroblastic tumour and Wegener’s granulomatosis. Methodology: A case of Wegener’s granulomatosis that mimicked an inflammatory myofibroblastic tumour is reported. The clinical presentation, staging of the disease, histology, and follow-up are analysed. Results: Histopathology of the temporal bone failed to provide an accurate diagnosis, even after immunocytochemical analyses. The diagnosis of Wegener’s granulomatosis was suspected after biopsy of a pulmonary mass and was confirmed by the presence of anti-neutrophil cytoplasmic antibodies in blood samples. Conclusion: Irrespective of the aetiology, a pseudotumour of the temporal bone should always be investigated by biology and radiology. Radiological investigations will allow staging of the disease and specific localisation for biopsies.
Issue:
Vol. 6, 2010, 2nd trimester


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Wegener’s granulomatosis of the temporal bone and skull base that mimicked an inflammatory myofibroblastic tumour: a case report