Title:
Young immunocompetent patient with oropharyngeal plasmablastic lymphoma
Authors:
O. Peetermans , A. L. Van de Velde , A. Dendooven , J. Huyskens , A. P. Gadisseur,P. Pauwels , P. M. Parizel , J. Peetermans, P. H. Van de Heyning , O. M. Vanderveken
Institutions:
Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium; Departments of Haematology, Pathology, Radiology, Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, Edegem; Department of Otorhinolaryngology and Head and Neck Surgery, AZ Klina, Brasschaat, Belgium.
Keywords:
Plasmablastic lymphoma, sleep apnoea, obstructive; oropharyngeal neoplasms; snoring; CHOP protocol [Supplementary Concept]
Pages:
151 - 155
Abstract:
Young immunocompetent patient with oropharyngeal plasmablastic lymphoma. Background: Plasmablastic lymphoma (PBL) is a rare tumour that most commonly occurs in the oral cavity in immunocompromised patients. Case report: A 35-year-old man presented with symptoms suggesting obstructive sleep apnoea syndrome (OSAS). Fiberoptic nasopharyngoscopy, contrast-enhanced computed tomography, and drug-induced sleep endoscopy revealed a mass in the oropharynx that completely obstructed the upper airway. Direct laryngoscopy was performed, and the lesion was excised using a CO l2ser. Anatomopathological examination and flow cytometric differentiation established a diagnosis of plasmablastic lymphoma (PBL). Postoperative chemotherapy resulted in complete response. Conclusions: Extra-oral PBLis very rare.This is the first published report of oropharyngeal PBL in an immunocompetent patient. This case emphasizes the importance of considering PBL as a differential diagnosis when an oropharyngeal tumour is present. Clinical ENT examination should include fiberoptic nasopharyngoscopy to detect any head and neck mass that may cause OSAS-related symptoms.
Issue:
Vol. 14, 2018, 2nd trimester


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Young immunocompetent patient with oropharyngeal plasmablastic lymphoma