Published In
B-ENT
Volume 5 · Issue 2
Pages: 115-118
History
Published Online: June 15, 2009
D. Tamiolakis
Department of Cytopathology
S. Barbagadaki
Department of Cytopathology
E. Proimos
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
S. Nikolaidou
Department of Cytopathology
T. S. Chimona
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
G. Georgiou
Department of Cytopathology
G. Perogamvrakis
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
C. E. Papadakis
ENT Department of Chania General Hospital, Chania, Crete, Greece
Tamiolakis, D., Barbagadaki, S., Proimos, E., Nikolaidou, S., Chimona, T. S., Georgiou, G., … Papadakis, C. E. (2009). Touch imprint cytological diagnosis of nodal Langerhans Cell Histiocytosis. B-ENT, 5(2), 115–118. Retrieved from https://www.b-ent.be/index.php/pub/article/view/244
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Abstract
Touch imprint cytological diagnosis of nodal Langerhans cell histiocytosis. Langerhans cell histiocytosis (LCH) is a rare neoplasm of the mononuclear phagocytic immunoregulatory system of unknown aetiology. Nodal involvement is uncommon. Cytological findings have seldom been described. A case study of LCH, arising in a submandibular node of a 42-year-old female, is reported. Fine needle aspiration smears were highly cellular and composed of a mixed cell population including eosinophils, lymphocytes, neutrophils, and macrophages. Imprint slides from the surgical specimen of the excised node exhibited Langerhans cells with nuclear grooves, leading to a diagnosis suggestive of LCH. Immunohistochemical staining of the node sections with CD1a and S-100 confirmed this diagnosis. In conclusion, cytology may favorably contribute to the diagnosis of LCH.
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Article Info
Published In
Journal
B-ENT
Volume / Issue
Volume 5 · Issue 2
Pages
115-118
History
Published Online
June 15, 2009
Affiliations
D. Tamiolakis
Department of Cytopathology
S. Barbagadaki
Department of Cytopathology
E. Proimos
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
S. Nikolaidou
Department of Cytopathology
T. S. Chimona
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
G. Georgiou
Department of Cytopathology
G. Perogamvrakis
Department of Ear-Nose-and Throat Surgery, General Hospital of Chania, Crete, Greece
C. E. Papadakis
ENT Department of Chania General Hospital, Chania, Crete, Greece
Cite this Article
Tamiolakis, D., Barbagadaki, S., Proimos, E., Nikolaidou, S., Chimona, T. S., Georgiou, G., … Papadakis, C. E. (2009). Touch imprint cytological diagnosis of nodal Langerhans Cell Histiocytosis. B-ENT, 5(2), 115–118. Retrieved from https://www.b-ent.be/index.php/pub/article/view/244
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