AFRS caused by S. commune diagnosed using specific antibodies and genetic identification

AFRS caused by S. commune diagnosed using specific antibodies and genetic identification. Background: Schizophyllum commune is a widespread species of fungus that grows on a variety of trees and decaying wood. It only rarely causes human disease such as allergic bronchopulmonary mycosis, fungal rhinosinusitis and allergic fungal rhinosinusitis (AFRS). AFRS caused by S. commune is the most unusual among these diseases. Case reports: we present two cases of S. commune-induced AFRS in a 34yearold and a 27-year-old woman diagnosed by elevated IgE antibodies, computed tomography findings and histopathological examinations of mucous and culture. Conclusion: the two patients showed positive specific IgE and IgG antibodies against S. commune using an enzymelinked immunosorbent assay. We confirmed a decrease in the values of specific antibodies after remission in a patient.