Cervical Ganglioneuromas – Unusual neck swellings

Objective: This study is a retrospective analysis of patients with cervical ganglioneuromas highlighting the clinical course, radiological features, and histopathological characteristics. Methods: A retrospective chart review of patients with cervical ganglioneuroma who were managed in a tertiary care center between January 2018 and December 2019 was performed. Data on their demographic profile, clinical presentation, management, and follow-up were collected. The relevant data of a representative case of cervical ganglioneuroma is described in detail along with the overall data of all the patients. Results: Three patients who had a diagnosis of biopsy proven ganglioneuroma from slowly progressive neck mass were included in this review. All 3 underwent complete surgical excision via transcervical approach. The tumor was seen to arise from the cervical sympathetic chain in all the cases with subsequent ipsilateral Horner’s syndrome in the postoperative period. No recurrence was detected in the mean follow-up period of 14 months. Conclusion: Cervical ganglioneuromas are slow-growing and noninvasive neck masses with surgical excision as the treatment of choice. Postoperative risk of Horner’s syndrome and lower cranial nerve weakness should be explained to the patients.