B-ENT
Original Article

The Effect of Cigarette Smoking on Nasal Septal Cartilage

1.

Department of Otolaryngology, Faculty of Medicine, Kahramanmaraş Sutcu Imam University, Kahramanmaraş, Turkey

2.

Department of Pathology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaraş, Turkey

3.

Department of Bioistatistics, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaraş, Turkey

B-ENT 2022; 18: 225-231
DOI: 10.5152/B-ENT.2022.22990
Read: 246 Downloads: 63 Published: 01 October 2022

Objective: This study aimed to reveal the effects of smoking on the septal cartilage on a histopathological basis.

Methods: This study was conducted between July 2020 and September 2021 at our Medical Faculty Hospital. A total of 62 subjects, aged between 18 and 55 years, with septoplasty/septorhinoplasty surgical indications were included in the study. After the mucoperichondrial flap elevation, 5 × 5 mm cartilage was taken from the anterior lower part of the septal cartilage while preserving the L-strut. Specimens were stained with hematoxylin and eosin, Alcian blue, and Masson’s trichrome stains. Chondrocyte viability and cartilage tissue status, type 2 collagen, and proteoglycan in matrix structure were assessed under a light microscope. Parameters such as chondrocyte clustering, cell morphology, and tissue appearance were assessed according to the International Cartilage Repair Society II and the groups were statistically compared.

Results: There were 43 men and 19 women, including 32 patients who had been smoking for at least 1 year and 30 non-smokers as the control group who were included in the study. The mean age was 28.01 ± 9.61 years, and the age range was between 18 and 50 years. There was no statistical difference between the groups in terms of age and gender distribution, and a statistical significant difference was found between the groups as a result of the comparison of histopathological data according to International Cartilage Repair Society II criteria.

Conclusion: According to the results of this study, there was no histopathologically negative effect of smoking on the septal cartilage

Cite this article as: Kara İ, Kılınç E, Doğaner A, et al. The effect of cigarette smoking on nasal septal cartilage. B-ENT. 2022;18(4):225-231.

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